Cloud303 Modernizes ImmuneID’s Genomic Data Architecture

High – Performance Computing

  • 30 September 2023
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About the Customer

ImmuneID is a groundbreaking company in the field of precision immunology, dedicated to unlocking the secrets of the human immune system through large-scale genomic analysis. Operating at the intersection of cutting-edge science and software innovation, ImmuneID faced challenges in data management, accessibility, and processing speed due to its earlier reliance on on-premises storage solutions.


ImmuneID specializes in precision immunology, using software to analyze vast amounts of genomic data. Their original setup had limitations: data was stored on-premises and was not easily accessible for concurrent use by their team. Cloud303 transformed ImmuneID’s data management by implementing a nightly backup to Amazon S3 and integrating AppStream 2.0 with R Studio for seamless data processing. This not only cut costs but also empowered scientists with real-time data access.

Problem Statement

ImmuneID was wrestling with data bottlenecks due to its reliance on on-premises storage solutions. Cloud303 - an AWS Premier Consulting Partner - stepped in to provide a cost-effective, scalable solution that would enable simultaneous, efficient data access for data analytics using RStudio.

Why Cloud303?

  • Demonstrated Expertise in HPC Cloud303 possesses specialized expertise in HPC, which is crucial for applications that require complex computational processes. This includes genomics sequencing, molecular modeling, and advanced simulations.
  • Robust Infrastructure The infrastructure provided by Cloud303 is tailored to meet the stringent performance, reliability, and scalability needs of HPC. Our team offers a robust ecosystem that can handle large-scale and intricate computations.
  • Exceptional Support and Security Cloud303 offers round-the-clock exceptional support, along with proven security protocols, to ensure that the sensitive data and complex workloads are managed in compliance with industry standards.
  • Proven Track Record Cloud303 has a strong history of successful partnerships within the life sciences industry. Our commitment to excellence, reliability, and client-focused solutions have made us a trusted partner.

Engagement Overview

Cloud303's engagements follow a streamlined five-phase lifecycle: Requirements, Design, Implementation, Testing, and Maintenance. Initially, a comprehensive assessment is conducted through a Well-Architected Review to identify client needs. This is followed by a scoping call to fine-tune the architectural design, upon which a Statement of Work (SoW) is agreed and signed.

The implementation phase kicks in next, closely adhering to the approved designs. Rigorous testing ensures that all components meet the client's specifications and industry standards. Finally, clients have the option to either manage the deployed solutions themselves or to enroll in Cloud303's Managed Services for ongoing maintenance, an option many choose due to their high satisfaction with the services provided.

Solution Provided

Upon an initial on-site assessment, Cloud303 connected ImmuneID's gene sequencer directly to Amazon S3, implementing a nightly automated backup system. To facilitate data analysis, we engineered an AppStream 2.0 golden image pre-loaded with RStudio.

However, the key innovation was in merging the capabilities of Amazon FSx and Amazon S3 within the AppStream 2.0 environment. This was accomplished using a combination of batch and PowerShell scripts along with a third-party application called RClone. This setup made it possible for scientists to transition data seamlessly between the high-throughput FSx and the cost-effective S3 storage solutions.

In technical terms, the configuration enabled a Windows file system mount of the S3 bucket, allowing easy data transfer to FSx whenever high-speed data manipulation was needed. We also rolled out a memory-optimized AppStream 2.0 fleet to ensure peak performance, especially when running complex R scripts.

Engineer Quote

Designing the solution for ImmuneID was akin to solving a multidimensional puzzle. Using a blend of AWS services, we achieved a solution that was both cost-effective and highly efficient.

Xhefri Toro Principal Solutions Architect (HPC and Life Sciences), Cloud303


ImmuneID’s new data ecosystem, powered by AWS and architected by Cloud303, has revolutionized their genomic data analytics. Scientists can now access and analyze data concurrently, thereby speeding up research timelines. This solution's elasticity allows ImmuneID to quickly scale their operations in line with business growth. Moreover, the cost savings have been substantial, enabling the re-allocation of financial resources to other critical research areas.

Scientists can now access and analyze data concurrently, thereby speeding up research timelines